Genome-wide cell-free DNA fragmentation in patients with cancer

Published in Nature, 2019

Recommended citation: Cristiano S et al. (2019). "Genome-wide cell-free DNA fragmentation in patients with cancer." Nature. 570(7761). http://rscharpf.github.io/files/Cristiano_et_al_Nature_2019.pdf

This paper describes an approach called DELFI to identify features of cell-free DNA fragmentation from shallow whole genome sequencing for early cancer detection.

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